exam question:
young black man with massive splenomegaly.no lymph nodes.asked for the single most likely diagnosis.
causes for splenomegaly:
1-Neoplastic
Lymphoproliferative: CCL, lymphoma
Myeloproliferative: CML, myelofibrosis
2-Inflammatory
Amyloidosis SLE
Sarcoidosis RA
3-Infective
Glandular fever
Hepatitis
Chronic malria/Brucelosis
SBE
4-Others
PRV cirrhosis
ITP storage disease
in which conditions the spleen is massively enlarged?
another exam question:
large isolated splenomegaly,no anaemia,no lymphadenopathy.
what is the most likely diagnosis?
how would you investigate?
another classification:
ReplyDeletemassive spleen:
CML
myelofibrosis
chronic mararia
kalazar
moderate spleen(2-4 fingers)
myeloproliferative disorders
lymphoproliferative disorders
just tipped:
myeloproliferative disorders
lymphoproliferative disorders
cirrhosis
inffection(glandualr fever,hepatitis,SBE
managment of huge splenomegaly
ReplyDeleteu/s if malignancy do CT scan
FBC for hypersplensim, pancytopenia
blood film for malaria and leshmaniasis and blast cells erythroblastc picture
bone marrow examination for CML and myelofibrosis
splenic biopsy if u suspect Guacher's disease
mgt of moderate spleen
U/S abdomen
FBC studies for hypersplensim and atypical lymphocyets fro glandular fever
bone marrow and lymph node biopsy
renal and liver function tests
viral hepatits screen
Rh factor
retics and screen for hemolytic anaemias
confirm splenomegaly.
ReplyDeletetell the examiner that you would like to ask about:Wt loss, fever and night sweats.
look for bone marrow aspiration/ trephine dressing or brusing over the iliac crest.
tell the examiner you would like to request a prepheral blood film.
CLL
ReplyDeletenike off white
ReplyDeletehermes birkin
lebron 16 shoes
pg 1
air jordan
supreme t shirt
moncler outlet
kd 12
hermes online
bathing ape
g6w22t2j92 s0i33v5b07 m3o51k5i72 f8g25n1y14 o4v11h2c85 c0m92n2a70
ReplyDelete