exam question:
patient with renal transplant and arteriovenous fistula,did not had palpable kidneys.
what are the causes of renal failure?
discussion about polycystic kidney disease(presentation/complications)
Polycystic kidney disease:
AD chromosome 16
Prevalence 1:1000
The third most common cause of CRF in the UK
see presentation below.
what are the most used immunosuppresive medications and its saide effects?
Dear friends and colleagues, Passing the MRCP UK is an important step in the medical career. PACES is the practical clinical exam and require a wide breadth of knowledge. This blog is a space to share materials, information and knowledge and I hope you find it useful. Am open for any ideas or suggestion and would value your contributions and comments. please visit my related pages on facebook and youtube. Best wishes, Dr Elmuhtady Said
PACES Stations
- General
- PACES station 1 abdomen
- PACES station 1 respiratory
- PACES station 2 history taking skills
- PACES station 3 cardiovascular
- PACES station 3 neurology
- PACES station 4 communication skill and ethics
- PACES station 5 (new station 5)
- PACES station 5 endocrinology
- PACES station 5 Fundus
- PACES station 5 rheumatology
- PACES station 5 skin
- record of PACES experience
Wednesday, 4 June 2008
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long-term drug treatment for the prevention of rejection is employed in all cases apart from living related donation from an identical twin.
ReplyDelete-Corticosteroids
-Azathioprine
Adverse effects include suppression of red cell and platelet production, an increased incidence of infections (particularly viral), and hepatotoxicity.
other side effects:
hypersensitivity reactions,dose-related bone marrow suppression,liver impairment, cholestatic jaundice and hair loss.
-Ciclosporin
Its introduction has revolutionized organ transplantation. Disadvantages include high cost and nephrotoxicity.
other side effects:
gastro-intestinal disturbances, gingival hyperplasia, hepatic dysfunction, anorexia; hypertension; tremor and headache.
-Tacrolimus
calcineurin inhibitor
Its side-effects are broadly similar to those of CSA except it is more diabetogenic
-Sirolimus
synergistic with CSA but lack nephrotoxicity
Its main side-effects are thombocytopenia and hyperlipidaemia.
complications of renal transplant:
ReplyDelete1-opportunistic infections
2-premature coronary artery disease
3-hypertention
4-lymphoma/skin cancer
5-glumerulonephritis
6-complications of steroid therapy
complications of APKD:
ReplyDeleterenal complications:
1-lion pain
2-anaemai
3-polycythemia
4-hypertension
5-renal failure
extrarenal complications:
cystic: cysts in other organs (liver, ovary,pancreas,spleen)
non-cystic:SAH,MVP
GIT:colonoic diverticulae
HIH
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other common drug used in renal tranasplant is mycophenalate and its side effects are diarrhea, nausea, vomiting, infections, leukopenia, and/or anemia.
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